Table 1.
Basic characteristics of Parkinson's disease (PD) or Non-PD before and after Propensity Score Model (PSM).
| Before PSM | After PSM | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| PD | Non-PD | PD | Non-PD | |||||||
| N | (%) | N | (%) | SMD | N | (%) | N | (%) | SMD | |
| Sample Size | 15,434 | 4,603,858 | 15,375 | 61,500 | ||||||
| Male | 9,144 | (59.2) | 2,553,140 | (55.5) | 0.077 | 9,113 | (59.3) | 36,452 | (59.3) | <0.001 |
| Age (y), Mean [SD] | 71.7 | [9.9] | 57.4 | [10.4] | 1.412 | 71.7 | [9.9] | 71.7 | [9.9] | <0.001 |
| Age group | ||||||||||
| 45–64 | 3,444 | (22.3) | 3,545,590 | (77.0) | 1.307 | 3,443 | (22.4) | 13,773 | (22.4) | <0.001 |
| 65 | 11,990 | (77.7) | 1,058,268 | (23.0) | 1.307 | 11,932 | (77.6) | 47,727 | (77.6) | <0.001 |
| Diagnostic year | ||||||||||
| 2004–2005 | 3,812 | (24.7) | 1,124,015 | (24.4) | 0.006 | 3,795 | (24.7) | 15,180 | (24.7) | <0.001 |
| 2006–2007 | 3,955 | (25.6) | 1,178,943 | (25.6) | 0.002 | 3,943 | (25.7) | 15,772 | (25.7) | <0.001 |
| 2008–2009 | 3,869 | (25.0) | 1,162,550 | (25.2) | 0.004 | 3,854 | (25.0) | 15,416 | (25.0) | <0.001 |
| 2010–2011 | 3,798 | (24.6) | 1,138,350 | (24.7) | 0.001 | 3,783 | (24.6) | 15,112 | (24.6) | <0.001 |
| Comorbidity, yes | ||||||||||
| HTN | 7,398 | (47.9) | 927,199 | (20.1) | 0.614 | 7,355 | (47.8) | 29,713 | (48.3) | 0.010 |
| DM | 3,206 | (20.8) | 430,198 | (9.3) | 0.324 | 3,175 | (20.7) | 12,586 | (20.5) | 0.005 |
| Hyperlipidemia | 2,602 | (16.9) | 429,938 | (9.3) | 0.224 | 2,582 | (16.8) | 10,014 | (16.3) | 0.014 |
| CHF | 460 | (3.0) | 28,559 | (0.6) | 0.178 | 426 | (2.8) | 1,524 | (2.5) | 0.018 |
| CAD | 2,429 | (15.7) | 210,937 | (4.6) | 0.376 | 2,393 | (15.6) | 9,579 | (15.6) | <0.001 |
| CLD | 2,316 | (15.0) | 241,166 | (5.2) | 0.328 | 2,283 | (14.8) | 9,089 | (14.8) | 0.002 |
| Renal disease | 660 | (4.3) | 58,419 | (1.3) | 0.184 | 644 | (4.2) | 2,362 | (3.8) | 0.018 |
| Inflammatory dx | 223 | (1.4) | 34,141 | (0.7) | 0.068 | 215 | (1.4) | 651 | (1.1) | 0.031 |
| Statin prescription before index date | 1,329 | (8.6) | 186,817 | (4.1) | 0.188 | 1,314 | (8.5) | 5,089 | (8.3) | 0.010 |
SMD (standardized mean difference) indicated the variable difference in means or proportions divided by standard error; imbalance defined as absolute value >0.1 dx, diagnosis; PD, Parkinson disease; HTN, hypertension; DM, diabetes mellitus; CHF, congestive heart failure; CAD, coronary heart disease; CLD, chronic lung disease.