Table 2.
50 significantly differentially abundant proteins between day 2 and day 5 of GC culture
| Protein name | Gene name | log2 fc | p value |
|---|---|---|---|
| Hydroxymethylglutaryl-CoA synthase, cytoplasmic | HMGCS1 | −4.20 | 1.82E-04 |
| Fibrinogen beta chain | FGB | −4.09 | 5.47E-03 |
| Fibrinogen alpha chain | FGA | −3.78 | 7.55E-03 |
| Signal recognition particle subunit SRP72 | SRP72 | −3.67 | 1.13E-02 |
| Lanosterol 14-alpha demethylase | CYP51A1 | −2.77 | 9.09E-03 |
| Fatty acid desaturase 2 | FADS2 | −2.56 | 6.55E-06 |
| Nucleolar RNA helicase 2 | DDX21 | −2.32 | 1.95E-03 |
| Protein transport protein Sec23B | SEC23B | −2.26 | 1.75E-03 |
| RNA polymerase II-associated protein 3 | RPAP3 | −2.26 | 7.72E-03 |
| LIM and cysteine-rich domains protein 1 | LMCD1 | −2.12 | 2.76E-03 |
| 60 S ribosomal protein L22-like 1 | RPL22L1 | −1.82 | 3.90E-03 |
| DnaJ homolog subfamily A member 1 | DNAJA1 | −1.78 | 9.18E-03 |
| Arf-GAP domain and FG repeat-containing protein 1 | AGFG1 | −1.78 | 9.24E-03 |
| Zinc transporter ZIP14 | SLC39A14 | −1.73 | 2.05E-03 |
| EH domain-containing protein 1 | EHD1 | −1.63 | 2.14E-03 |
| A-kinase anchor protein 2 | AKAP2 | −1.61 | 8.69E-03 |
| Proteasome-associated protein ECM29 homolog | ECM29 | −1.56 | 1.45E-03 |
| Serotransferrin | TF | −1.48 | 6.79E-03 |
| E3 ubiquitin-protein ligase UBR4 | UBR4 | −1.32 | 3.35E-03 |
| Coiled-coil domain-containing protein 47 | CCDC47 | −1.28 | 6.43E-03 |
| Plasminogen activator inhibitor 2 | SERPINB2 | −1.27 | 2.07E-03 |
| Golgi membrane protein 1 | GOLM1 | −1.21 | 3.63E-03 |
| Neuroblast differentiation-associated protein AHNAK | AHNAK | −1.19 | 3.39E-04 |
| ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial | CLPX | −1.18 | 2.52E-03 |
| Vigilin | HDLBP | −1.08 | 2.81E-03 |
| Histone deacetylase 6 | HDAC6 | −1.00 | 1.22E-04 |
| Farnesyl pyrophosphate synthase | FDPS | −0.93 | 9.37E-04 |
| Beta-hexosaminidase subunit beta | HEXB | 0.91 | 2.88E-04 |
| N-acetylglucosamine-6-sulfatase | GNS | 0.94 | 7.76E-04 |
| Cathepsin D | CTSD | 1.03 | 9.81E-04 |
| Putative phospholipase B-like 2 | PLBD2 | 1.04 | 2.91E-03 |
| Prosaposin | PSAP | 1.06 | 2.20E-03 |
| Integrin alpha-1 | ITGA1 | 1.10 | 1.94E-03 |
| Sphingomyelin phosphodiesterase | SMPD1 | 1.17 | 6.37E-03 |
| Adenylate kinase isoenzyme 1 | AK1 | 1.17 | 5.85E-03 |
| ATP synthase mitochondrial F1 complex assembly factor 1 | ATPAF1 | 1.26 | 5.86E-03 |
| Granulins | GRN | 1.34 | 5.82E-04 |
| Beta-hexosaminidase subunit alpha | HEXA | 1.37 | 4.81E-04 |
| Protein FAM162A | FAM162A | 1.38 | 6.68E-04 |
| Tissue alpha-L-fucosidase | FUCA1 | 1.58 | 3.36E-03 |
| Dipeptidyl peptidase 2 | DPP7 | 1.62 | 1.66E-03 |
| Four and a half LIM domains protein 2 | FHL2 | 1.64 | 3.14E-03 |
| Fatty acid-binding protein, heart | FABP3 | 1.70 | 2.36E-03 |
| Alpha-N-acetylglucosaminidase | NAGLU | 1.80 | 9.35E-03 |
| Vacuolar protein sorting-associated protein VTA1 homolog | VTA1 | 1.83 | 7.35E-03 |
| Lysosomal protective protein | CTSA | 1.85 | 3.72E-06 |
| Unconventional myosin-VI | MYO6 | 1.97 | 1.89E-03 |
| Arylsulfatase B | ARSB | 2.43 | 3.38E-04 |
| Acid ceramidase | ASAH1 | 2.57 | 6.39E-03 |
| Mammalian ependymin-related protein 1 | EPDR1 | 3.50 | 1.09E-03 |
Log2 fold change and p values of the proteins highlighted in the volcano plot shown in Fig. 2