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. 2019 Feb 11;10:701. doi: 10.1038/s41467-019-08605-3

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — Hectd3 interacts with and promotes Stat3 polyubiquitination. a Immunoblot of Stat3 and ubiquitin following polyubiquitinated protein enrichment of extracts from dLN CD4⁺ T cells of Hectd3^−/− or wild-type (WT) mice, 13 days following EAE induction. b Immunoblot of Hectd3 and Stat3 following Stat3 or IgG immunoprecipitation of protein extracts from dLN CD4⁺ T cells of WT mice 13 days following EAE induction. a, b Immunoblots are representative of three independent experiments. Source data are provided as a Source Data file