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. 2019 Feb 11;9:1761. doi: 10.1038/s41598-018-37981-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Gene expression levels of OCT-4 in cultured hDPSCs (A), hGFs (B) and hFFs (C) for 0, 7, 14 and 21 days in presence of OM and AM, relative to the respective expression levels at T0. (D) Expression levels of OCT-4 normalized for OCT-4 expression in hDPSCs at T0. Asterisks: Mann Whitney – U/Wilcox Rank Sum Test, *p < 0.05; **p < 0.01. Colour of asterisks onto each column indicates the column used for the comparison. Abbreviations: hDPSCs, human dental pulp stem cells; hFF, human foreskin fibroblasts; hGF, human gingival fibroblasts; OM, osteogenic medium; AM, adipogenic medium.