Table 2.

A summary of predictive performance in the training and independent test sets of the prediction models with averaged coefficients

	Training set (Cologne)		Independent test set (Rotterdam)
Schizophrenia patients	60		9
Controls	77		12
(a)	Training set		Independent test set
	Number of features	AUC	AUC
Model with >0.80 inclusion fraction	6	0.807 Males only 0.851 Females only 0.751	Males only 0.880
Model with relative feature importance >0.90	8	0.821 Males only 0.863 Females only 0.773	Males only 0.917
(b)
Model with >0.80 inclusion fraction	17 with 5 first-order interactions with sex	0.858 Males only 0.890 Females only 0.819	Males only 0.889
Model with relative feature importance >0.90	13 with 3 first-order interactions with sex	0.854 Males only 0.887 Females only 0.818	Males only 0.815

Model selection (a) did not consider first-order interactions with sex and (b) did allow for first-order interactions with sex