Fig. 4. Measures of prepulse inhibition are not significantly impacted by early truncation of Disc1.

a Quantification of prepulse inhibition in P84 Disc1 svΔ2 rats and wild-type control rats. b Quantification of startle response magnitude in P84 Disc1 svΔ2 rats and wild-type control rats. c Quantification of latency from trial onset to startle response for male wild-type and male Disc1 svΔ2 rats. **p-value < .01; ***p-value < .001, by three-way ANOVA with Tukey’s post hoc tests. d Quantification of latency from trial onset to startle response for female wild-type and female Disc1 svΔ2 rats. e Quantification of latency from trial onset to maximum startle response for male wild-type and male Disc1 svΔ2 rats. f Quantification of latency from trial onset to maximum startle response for female wild-type and female Disc1 svΔ2 rats. g Quantification of habituation to startle-alone trials. Error bars denote mean ± s.e.m. For control male group, n = 24. For control female group, n = 18. For Disc1 svΔ2 male and female groups, n = 15