Table 1.

Comparison of Therapeutic Outcomes between a Meta-Analysis and Retrospective Multicenter Cohort Study

	Meta-analysis published in 2014 [4]	Retrospective multicenter cohort study [5]
Included studies or centers (published year or duration of enrollment)	14 studies (2009–2014)	8 centers (2006–2015)
Enrolled cases	972 EGC-UH	275 EGC-UH
En bloc resection rate (rate of lesions that met expanded criteria)	92.1% (91.2%)	92.4% (95.4%)
Complete resection rate (rate of lesions that met expanded criteria)	77.5% (85.6%)	80% (91.7%)
Curative resection rate (rate of lesions that met expanded criteria)	61.4% (79.8%)	36.4% (91.7%)
Recurrence rate (rate of lesions that met expanded criteria in a retrospective multicenter study)	7.6% (95% confidence interval: 3.4%–16%) (range of follow-up duration: 13.5–101.9 mo)	10.2% (9.2%) (median follow-up with interquartile range: 3.96 yr (1.11–5.09 yr)

En bloc resection is defined as complete removal of cancer in a single piece without fragmentation. Complete resection is defined as removal of cancer with no neoplastic components at the lateral or vertical margins and without lymphovascular invasion on microscopic examination. Curative resection is defined as removal of cancer with intramucosal lesions measuring ≤20 mm and without ulceration, neoplastic components at the lateral or vertical margins, or lymphovascular invasion. [3,5]

EGC-UH, early gastric cancer with undifferentiated-type histology.