Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Components of oncogenic survival signaling in PCNSL. Activation of TLR4/MYD88 and the BCR complex may contribute to prosurvival signaling via NF-κB. Enhanced production of IL-4/10 also contributes to survival signals along with the JAK/STAT pathway.
Abbreviations: BCR, B cell receptor; IL-4, interleukin-4; IL-10, interleukin-10; TLR, Toll-like receptor; NF-kB, nuclear factor-kB; JAK, Janus kinase; STAT, signal transducer and activator of transcription.
