Figure 3:

(a) A histogram of the messaging volume. The purple vertical line indicates the median number (86) of messages communicated between healthcare providers. (b) The LOWESS smoothed curves, along with the 95% confidence interval, of the number of messages sent per 6-month period (messaging rate) for patients who completed treatment protocol (green) and patients who discontinued medications (red), respectively. 25% of the data was applied to estimate each data point. (c) Log-transformed messaging rate with respect to the probability of a medication discontinuation event (after smoothing with a moving average).