Table 5:

User Persona 2 - Carl, Clinical Pharmacist

Tasks	Carl is a clinical pharmacist who spends 2-3 hours per week researching NPDIs or DDIs and one hour per week on related websites.
Information Needs	Carl selects four areas of interaction information in a pharmacokinetic NPDI database that he sees as highly important. These include the quantitative clinical parameters measuring the risk/extent of NPDIs, mechanistic understanding of NPDIs and DDIs, the bioanalytical methodology used for NPDI studies, and the rationale and validation for the NPDI or DDI studies. Carl also requests information pertaining to the “overlapping physiologic reactions with the target patient population.”
	Carl selects four categories of important background information to include in a NPDI database: (1) whether or not the NPDI study results can be extrapolated to other NPs, (2) whether or not the NPDI study results with a probe drug can be extrapolated to other drugs, (3) overall clinical relevance, and (4) documentation.
Information Seeking	Carl would like a NPDI database to include a search option, search glossary, and news sections highlighting new publications on NPDIs. Carl believes the ideal website would allow for him to analyze if a certain NP will interact with a patient's current or prospective drugs or medical condition. Carl states that the level of risk and clinical relevance are important factors to consider. He notes the prominence of quality research that addresses problems with NPs, such as “the presence of multiple ingredients in the products, and concern for the lack of GMP quality of these products or adulteration with prescription medications or other supplements.”