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. Author manuscript; available in PMC: 2019 Feb 12.
Published in final edited form as: Chem Res Toxicol. 2006 Nov;19(11):1435–1440. doi: 10.1021/tx0600907

Figure 3.

Figure 3.

(A) Comparison of the percentage of mutational types for all (large and small) colonies produced in mouse lymphoma cells treated with control, UVA, RP + UVA, AR + UVA, and 5,6-epoxy-RP + UVA. The data for control, UVA alone, and RP + UVA are from our previous study (19). (B) Different types of mutations shown by histograms indicating the range of LOH, at the same scale as used in the ideogram of mouse chromosome 11. The loci that were analyzed for LOH (Tk1, D11Mit42, D11Mit29, and D11Mit74) are marked. The ruler in centimorgans indicates the distance from the top of the chromosome. Type 1 mutation, non-LOH; type 2, LOH at Tk locus only; type 3, LOH extending to D11Mit42 (about 6 cM); type 4, LOH extending to D11Mit29 (about 38 cM); and type 5, LOH extending to the top of chromosome 11.