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. 2019 Feb 11;12:14. doi: 10.1186/s13041-019-0432-9

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — The effect of DA-JC1 on Aβ31–35-induced circadian rhythm disorder in mice. (a) Representative locomotor activity records of each group. (b) The free-running period of the locomotor activity rhythm in each group. (c) The average activity in DD of all the mice at each one-hour interval in the actogram. Data were expressed as means ± SEM (n = 6 per group). *P < 0.05 compared with the control group; #P < 0.05 compared with the Aβ31–35 group