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. 2019 Feb 11;12:14. doi: 10.1186/s13041-019-0432-9

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — The effect of interference in Per2 using lentivirus on DA-JC1’s improvement of abnormal learning and memory capacity induced by Aβ31–35. (a) The escape latency in hidden platform acquisition testing at each day. (b) The percentage of time spent and the percentage of distance traveled in the four quadrants. Zone-NE indicates the target quadrant. (c) Representative Western blot and quantification analysis of SYP and GAP-43. Data are expressed as means ± SEM (n = 6 per group). *P < 0.05 compared with the control group