Fig. 1.

Dynamic laser light scattering particle size analysis of our empty Nano control without any miR and Nano miR-200c showing the Z-average size distribution of the particle and micro-fluidization results, with a dramatic decrease in particle size, and demonstrating the heterogeneity of particle size, even within what appears to be a homogeneous distribution. a- The size of our empty Nano vehicle; b- The size of the vehicle plus miR-200c; c- The Zeta potential of empty Nano; and d- The Zeta potential of the Nano miR-200c encapsulated gene