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. 2019 Feb 11;19:136. doi: 10.1186/s12885-019-5337-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 9 — In situ hybridization analyses of the expression patterns of miRs- 200c, 221, 222, 346, and 1195 and Nkx2.1 in developmental CD1, phosphorylation mutant and Kras mice. a- Comparison of the levels of miR-200c, 221, 222, and 346 in our mouse models at E-11.5 in whole embryo, liver, lung, and dorsal root ganglion. miR-346, for instance, was expressed specifically in the liver and dorsal root ganglion. b- E-19.5 showed similar patterns of expression in normal mouse lung epithelium in comparison to Kras. c- In situ hybridization of Nkx2.1 mRNA at E11.5 confirmed the similar epithelial pattern to miR-1195