Table 1.
Comparison of biomarker levels among patients with achalasia, EoE, and GERD
| Biomarker | Achalasia (n = 53) | EoE (n = 22) | GERD (n = 21) | P-valuea |
|---|---|---|---|---|
| Median (IQR) | Median (IQR) | Median (IQR) | ||
| IL-6 | 2.45 (2.4) | 1.71 (1) | 2.05 (3.7) | 0.0158 Achalasia vs EoE < 0.05b |
| IL-12p70 | 1.45 (0.9) | 2.35 (1.4) | 1.19 (0.98) | 0.091 |
| IL-17 | 8.14 (5.6) | 9.96 (7.9) | 5.89 (6.9) | 0.052 |
| IL-22 | 12.4 (5.7) | 10.28 (3.3) | 11.35 (4.2) | 0.097 |
| IL-23 | 23.86 (15.0) | 26.58 (16.9) | 16.45 (12.8) | 0.10 |
| TNF-α | 4.06 (1.15) | 3.97 (2.1) | 4.17 (1.3) | 0.53 |
| IFN-γ | 5.27 (1.7) | 5.78 (1.5) | 6.12 (1.9) | 0.22 |
a - Kruskal–Wallis rank sum test to compare overall differences between groups
b - post-hoc Dunn’s test p-value for pairwise comparison