Fig. 7.
SHH is a miR-193a target. a SHH protein levels were reduced in miR-193a-overexpressing cells compared with vector controls (p < 0.05). b SHH mRNA levels were reduced in miR-193a-overexpressing A549 cells (p < 0.05). c miR-193a bound to SHH-3′UTR-wt. Binding was blocked by SHH-3′UTR-mt. d Dual Luciferase Reporter assays indicated that the miR-193a mimic bound SHH-3′UTR-wt but not the ones that were mutated (p < 0.05)