Fig. 1.

Effects of chlorpyrifos administration on body composition. C57Bl/6 (a–d) and CD-1 (ICR) (e–h) mice were fed either a normal-fat diet (NFD) or high-fat diet (HFD) for 12 weeks. NCPF and HCPF mice were treated daily with 5 mg/kg chlorpyrifos. NFD and HFD control mice were gavaged with vehicle (corn oil). Effects of chlorpyrifos treatment on body weight (a, e), percent of body weight change (b, f), epididymal fat pad weight (c, g), and epididymal fat pad content of whole body weight (d, h) were measured (n = 8). Data are expressed as the mean ± SEM.*P < 0.05 vs. NFD group; ^#P < 0.05 vs. HFD group. NFD normal-fat diet, NCPF normal-fat diet + chlorpyrifos, HFD high-fat diet, HCPF high-fat diet + chlorpyrifos