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. 2019 Feb 5;13:18. doi: 10.3389/fncel.2019.00018

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Copyright © 2019 He, Yang, Zhang, Hou, Xu, Hu, Xu, Wang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of SMI on striatal dopamine D1 and D2 receptor density and protein level in chronic MPTP/probenecid-lesioned mice. (A) D1 receptor density, assessed by ³H-SCH23390 (n = 9). Panel (B) D2 receptor density, assessed by ³H-spiperone (n = 9). Panel (C) shows representative western blot bands of D1 and D2 receptor. Panels (D,E) show relative protein expression levels were quantified by densitometry analysis using Image J software on D1 and D2 receptor bands (n = 4). Data are expressed as mean ± SEM. *P < 0.05 and **P < 0.01, respectively as compared with untreated model group, respectively.