Table 2.
Group | Outcome | Presentation blood glucose (mmol/L) | Events/patients | Rate per 100 pyrs (95% CI) | Adjusted HR (95%CI) | P-value |
---|---|---|---|---|---|---|
Pre-existing diabetes | All-cause mortality | 3.9–6.1 | 81/1271 | 6.4 (5.1–7.9) | Referent | NA |
>6.1–7.8 | 105/1457 | 7.2 (5.9–8.7) | 1.13 (0.82–1.56) | 0.446 | ||
>7.8–9.4 | 78/1254 | 6.2 (4.9–7.8) | 1.21 (0.86–1.70) | 0.284 | ||
>9.4–11.1 | 56/981 | 5.7 (4.3–7.4) | 0.96 (0.66–1.39) | 0.821 | ||
>11.1 | 196/2286 | 8.6 (7.4–9.9) | 1.48 (1.10–2.00) | 0.010 | ||
Cardiovascular mortality | 3.9–6.1 | 44/1271 | 3.5 (2.5–4.7) | Referent | NA | |
>6.1–7.8 | 62/1457 | 4.3 (3.3–5.5) | 1.21 (0.80–1.83) | 0.373 | ||
>7.8–9.4 | 46/1254 | 3.7 (2.7–4.9) | 1.16 (0.74–1.82) | 0.517 | ||
>9.4–11.1 | 31/981 | 3.2 (2.2–4.5) | 0.90 (0.55–1.48) | 0.683 | ||
>11.1 | 114/2286 | 5.0 (4.1–6.0) | 1.44 (0.97–2.14) | 0.068 | ||
No pre-existing diabetes | All-cause mortality | 3.9–6.1 | 270/4023 | 6.7 (5.9–7.6) | Referent | NA |
>6.1–7.8 | 273/3089 | 8.8 (7.8–10.0) | 1.26 (1.05–1.50) | 0.013 | ||
>7.8–9.4 | 150/1171 | 12.8 (10.8–15.0) | 1.47 (1.18–1.82) | <0.001 | ||
>9.4–11.1 | 60/468 | 12.8 (9.8–16.5) | 1.41 (1.04–1.90) | 0.027 | ||
>11.1 | 83/524 | 15.8 (12.6–19.6) | 1.50 (1.11–2.02) | 0.008 | ||
Cardiovascular mortality | 3.9–6.1 | 182/4023 | 4.5 (3.9–5.2) | Referent | NA | |
>6.1–7.8 | 190/3089 | 6.2 (5.3–7.1) | 1.28 (1.03–1.59) | 0.024 | ||
>7.8–9.4 | 103/1171 | 8.8 (7.2–10.7) | 1.54 (1.18–1.99) | 0.001 | ||
>9.4–11.1 | 44/468 | 9.4 (6.8–12.6) | 1.64 (1.16–2.33) | 0.006 | ||
>11.1 | 58/524 | 11.1 (8.4–14.3) | 1.51 (1.05–2.18) | 0.025 |
pyrs, person-years.