Table 2.

Collection of developmental, behavioral, and medical information on child and family by time point.

Forms and Source		Prenatal (Trimesters)			Postnatal
Forms	Source	1st	2nd	3rd	2 Weeks	3 Months	6 Months	12 Months	24 Months	36 Months
Family Developmental/Mental Health
Social Responsiveness Scale	Constantino 2002; Constantino et al. 2003		mother, father, & probanda							sibling
Early Developmental Questionnaire	Ozonoff et al. 2005		probanda							siblingb
Social Communication Questionnaire	Rutter et al. 2003									sibling, proband
Maternal Perceived Stress Scale	Cohen et al. 1983	motherc	motherc	mother	mother	mother	mother	mother	mother	mother
Family Characteristics Questionnaire	UC Davis study team					all first degree relatives
Medical
Family Medical History (includes physical and mental health)	UC Davis study team					mother
Autoimmune survey	UC Davis study team					first and second degree relatives
Medical records	Health care providers		mother, sibling, & probandad		mother, siblinge			sibling	sibling	sibling
Autism-Related
Autism Observation Scale for Infants	Bryson et al. 2008						sibling	sibling
Infant Toddler Checklist—Communication and Symbolic Behaviors Scale Developmental Profile	Wetherby et al. 2002						sibling	sibling
Modified Checklist for Autism in Toddlers	Robins et al. 2001								sibling
Autism Diagnostic Observation Schedule	Lord et al. 2000a, b								sibling	sibling
Autism Diagnostic Interview Revised	Lord et al. 1994									siblingb
Examiner Ratings of Social Engagement	Ozonoff et al. 2010						sibling	sibling	sibling	sibling
Social Responsiveness Scale	Constantino 2002; Constantino et al. 2003									sibling
Cognitive, Adaptive & Behavioral
Mullen Scales of Early Learning	Mullen 1995						sibling	sibling	sibling	sibling
Vineland Adaptive Behavior Scales	Sparrow et al. 1984									sibling
Child Behavior Checklist	Achenbach 1991, 1994									sibling
Children’s Sleep Habits Questionnaire	Owens et al. 2000								sibling	sibling
Intervention History	UC Davis study team								sibling	sibling
Parent Concerns	Ozonoff et al. 2009					sibling	sibling	sibling	sibling	sibling

Note: Shaded items are self-administered by the primary caregiver (generally the mother), others are administered by, or with assistance from staff. Proband is the affected older sibling; Sibling is the younger sibling born during the study.

^aAdministered once at some point during the pregnancy (could be any trimester).

^bOnly for younger siblings showing signs of ASD.

^cIf possible, depending on timing of enrollment.

^dAll records for proband obtained upon study entry.

^eMaternal is labor and delivery.