Table 2.
Treatment of solid tumors preceding hematologic malignancy
| Case no. | Age (years)/sex | Solid malignant neoplasms | Treatment received |
|---|---|---|---|
| 1 | 34/F | RT breast ductal carcinoma | Docetaxel + capecitabine × 4 courses (C), 5-fluorouracil, epirubicin, cyclophosphamide × 4 C, RT segmental mastectomy with axillary node dissection, XRT 5000 cGy in 25 fractions and tamoxifen |
| RT thigh spindle cell cancer | Adriamycin + ifosfamide × 6 C, XRT 5000 cGy in 25 fractions, and surgical resection | ||
| Sarcoma of RT axillary region | Gemcitabine + docetaxel × 5 C, and surgical resection | ||
| 2 | 32/F | LT maxillary sinus osteosarcoma | Doxorubicin + cisplatin × 4 C, and LT maxillectomy |
| Bilateral papillary thyroid cancer | Thyroidectomy with LT-sided paratracheal neck dissection | ||
| 3 | 42/M | Pleomorphic sarcoma of RT hip and gluteal region | Adriamycin + ifosfamide × 6 C, XRT 5000 cGy in 25 fractions, and radical resection of sarcoma |
| 4 | 28/F | RT breast pleomorphic spindle cell cancer | Adriamycin + ifosfamide × 6 C, XRT 5000 cGy in 25 fractions, and bilateral mastectomy |
| LT breast DCIS | |||
| 5 | 50/F | RT breast mixed ductal and lobular carcinoma | Modified radical mastectomy, 5-fluorouracil, doxorubicin, cyclophosphamide × 6 C, and prophylactic XRT to LT breast |
| High-grade osteosarcoma of chest wall | Adriamycin + ifosfamide and docetaxel + gemcitabine × 2 C, RT chest wall resection, and methotrexate × 8 C | ||
| 6 | 34/F | None | |
| 7 | 24/M | Astrocytoma | Surgical resection |
(RT) Right, (LT) left, (DCIS) ductal carcinoma in situ, (XRT) external beam radiation therapy, (C) cycle.