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cLog D, log D, and Monkey and Human Plasma Free Fractions of COX-1-Selective Radioligands
| radioligand | clog D | log D (n = 6) | monkey fP (n = 3) | human fP (n = 3) |
|---|---|---|---|---|
| [11C]PS1 | 3.72 | 3.29 ± 0.00 | 0.042 ± 0.001 | 0.036 ± 0.001 |
| [2H2,18F]PS2 | 3.84 | 3.26 ± 0.01 | 0.039 ± 0.001 | 0.021 ± 0.000 |
| [11C]PS13 | 3.59 | 4.26 ± 0.04 | 0.011 ± 0.001 | 0.002 ± 0.000 |
