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(A) Frequencies of genes with sequence variants identified by whole exome sequencing and targeted sequencing in IR-exposed (black) and unexposed (white) MPN patients negative for usual driver mutations in JAK2, MPL and CALR genes. (B) Pathways potentially affected in 12 IR-exposed (black) and 16 unexposed (white) MPN patients negative for usual driver mutations in JAK2, MPL and CALR genes. IR: Ionizing Radiation; MPN: myeloproliferative neoplasms.
