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. Author manuscript; available in PMC: 2019 Feb 12.
Published in final edited form as: J Urol. 2015 Mar 3;194(2):547–555. doi: 10.1016/j.juro.2015.02.2918

Figure 5.

Figure 5.

SW780 cells treated with cisplatin (Cis), AR-42 (AR) or cisplatin plus AR-42 for 24 hours showed enhanced apoptosis on annexin V and PI staining followed by flow cytometry (A). Annexin V+PI− cells were considered early apoptotic cells (blue bars). Annexin V+PI+ cells were considered late apoptotic cells (red bars). Live cells were unstained (green bars). Ctrl, control. Single asterisk indicates statistical significance between all populations and other treatment groups (1-way ANOVA p <0.05). Double asterisks indicate statistical significance between all populations and other treatment groups except early apoptotic cells between AR-42 and AR-42 plus cisplatin (1-way ANOVA p <0.05). SW780 cells were treated with varying cisplatin and AR-42 concentrations for 48 hours (B). Viability was assessed by MTT incorporation. Curves indicate mean of triplicate preparations and represent 2 independent experiments (not significant according to 1-way ANOVA p <0.05).