Effect of treatment on the (A) Discrimination Index (DI) (Group x Time interaction: F(2.16)=23.33, P<0.0001) and (B) Recognition Index (RI) (Group × Time interaction: F(2.16)=54.33, P=0.0003) of aged wistar rats, at 21 days post-stroke (n = 7 animals/group). Repeated measures ANOVA mixed models were used to examine differences in outcomes, between the groups over time. Bars and error bars indicate mean and SEM. Statistical significance is denoted by *P<0.001 for post hoc pair-wise comparisons from baseline and #P<0.001 for post hoc pair-wise comparisons “between groups” post-stoke, using the Bonferroni adjusted alpha.