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Summary of the rat strains and the doses of pharmacological compounds used in experiments performed for the evaluation of combined treatments with memantine and PHA-543613.
| Strain | Vehicle | Memantine (mg/kg) | PHA-543613 (mg/kg) | Scopolamine (mg/kg) | |
|---|---|---|---|---|---|
| Experiment 1 | Long Evans | Saline | 0.003 | 0.1 | 0.5 |
| Experiment 2 | Long Evans | Saline | 0.03 | 0.1 | 0.5 |
| Experiment 3 | Wistar | Saline | 0.1 | 0.3 | 0.5 |
| Experiment 4 | Wistar | Saline | 0.3 | 0.3 | 0.5 |
