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. 2019 Feb 12;6:190013. doi: 10.1038/sdata.2019.13

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Copyright © 2019, The Author(s)

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ The Creative Commons Public Domain Dedication waiver http://creativecommons.org/publicdomain/zero/1.0/ applies to the metadata files made available in this article.

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a–c represent the 3-D PCA plot, 3-D sPLS-DA plot, and the heatmap of the miRNAs expression in the bovine sera, exosomes and 11 different tissues. Each tissue was displayed using different colors. PCA = principal component analysis; sPLS-DA = sparse partial least squares-discriminant analysis. The 11 tissues include dairy cow rumen, duodenum, jejunum, liver and mammary gland, beef cattle duodenum, distal jejunum, proximal jejunum, cecum, spiral colon and descending colon.