Table 2.
Outcomes | Estimates by cohort | Pairwise cohort comparisons | ||||
---|---|---|---|---|---|---|
| ||||||
PreTT (2002–2005) n=1,466 | TTi (2006–2008) n=1,158 | TTii (2009–2010) n=806 | TTi vs PreTT | TTii vs PreTT | TTii vs TTi | |
| ||||||
Costs, $ | ||||||
Inpatient costs | 9,978 | 10,948 | 9,503 | 970 | −475 | −1,445 |
Outpatient costs | 2,802 | 3,157 | 2,794 | 356 | −8 | −363 |
Other drug costs | 2,898 | 4,001 | 3,682 | 1,103 | 784 | −319 |
TT costs | 1,217 | 11,817 | 14,058 | 10,600 | 12,842 | 2,242 |
Total costs | 16,894 | 29,922 | 30,037 | 13,028 | 13,143 | 115 |
Mean survival, years | 1.45 | 1.62 | 1.83 | |||
LYG | 0.17 | 0.39 | 0.22 | |||
Cost per LYG, $ | 78,656 | 34,132 | 523 |
Notes: All costs are represented in US$.
Abbreviations: LYG, life-years gained; mRCC, metastatic renal cell carcinoma; PreTT, pre-TT introduction (patients diagnosed with mRCC 2002–2005); TT, targeted therapies; TTi, early TT introduction (patients diagnosed with mRCC 2006–2008); TTii, late TT introduction (patients diagnosed with mRCC 2009–2010).