Table 2.

Comparison of methylation levels in CpG sites between PTC and adjacent normal tissues

CpG sites	Number of pairs	Tissue types	Mean methylation level	P-value
9-CpG-1, 2, 3	10	PTC	0.292±0.097	<0.001
		NT	0.128±0.168
9-CpG-5, 6	10	PTC	0.273±0.078	<0.001
		NT	0.084±0.020
9-CpG-19, 20	10	PTC	0.272±0.068	<0.001
		NT	0.127±0.031
9-CpG-21	10	PTC	0.281±0.060	<0.001
		NT	0.121±0.059
9-CpG-35	10	PTC	0.303±0.220	0.005
		NT	0.068±0.084
9-CpG-36, 37	10	PTC	0.287±0.035	<0.001
		NT	0.127±0.032
9-CpG-38, 39	10	PTC	0.244±0.068	<0.001
		NT	0.084±0.020
9-CpG-40, 41	10	PTC	0.392±0.056	<0.001
		NT	0.195±0.106
9-CpG-44	10	PTC	0.292±0.055	<0.001
9-CpG-47	10	NT	0.121±0.059	<0.001
		PTC	0.299±0.045
15-CpG-8	10	NT	0.121±0.056	0.009
		PTC	0.463±0.096
15-CpG-13	10	NT	0.0279±0.172	<0.001
		PTC	0.479±0.050
		NT	0.299±0.090

Notes: CpG sites represent region number-CpG site numbers. Mean methylation level is represented as the mean value ± SD.

Abbreviations: NT, normal tissue; PTC, papillary thyroid carcinoma.