Table 3.

Ongoing studies

Study	N° patients	Study group	Control group	Primary endpoint	Phase
NeoPembrOv42	45	NACT: Carboplatin + paclitaxel q3w + pembrolizumab 200 mg ADJ: Carboplatin + paclitaxel q3w + bevacizumab 15 mg/kg q3w + pembrolizumab 200 mg M: Pembrolizumab 200 mg + bevacizumab 15 mg/kg q3w (max 15 m)	NACT: Carboplatin + paclitaxel q3w ADJ: Carboplatin + paclitaxel q3w + bevacizumab 15 mg/kg q3w + bevacizumab 15 mg/kg q3w max 15 m)	CRR	II
IMagyn05043	1,300	NACT: Carboplatin + paclitaxel q3w + bevacizumab 15 mg/kg q3w + atezolizumab 1,200 mg q3w ADJ: Carboplatin + paclitaxel q3w + bevacizumab 15 mg/kg q3w + atezolizumab 1,200 mg q3w M: Bevacizumab 15 mg/kg q3w + atezolizumab 1,200 mg q3w	NACT: Carboplatin + paclitaxel q3w + bevacizumab 15 mg/kg q3w ADJ: Carboplatin + paclitaxel q3w + bevacizumab 15 mg/kg q3w M: Bevacizumab 15 mg/kg q3w	PFS OS	III
NCT0052001344	60	ADJ: Carboplatin + paclitaxel q3w + bevacizumab 15 mg/kg q3w for 6 cycles M: Bevacizumab 15 mg/kg q3w for 1 year + erlotinib 150 mg/day for 1 year	ADJ: Carboplatin + paclitaxel q3w + bevacizumab 15 mg/kg q3w for 6 cycles M: Bevacizumab 15 mg/kg q3w for 1 year	PFS	II
MITO 2545	234	ARM 1: ADJ: Carboplatin + paclitaxel q3w + bevacizumab 15 mg/kg q3w for 6 cycles M: Bevacizumab 15 mg/kg q3w for 22 cycles + rucaparib 600 mg BID q28 ARM 2: ADJ: Carboplatin + paclitaxel q3w M: Rucaparib 600 mg BID q28 for 2 years	ADJ: Carboplatin + paclitaxel q3w + bevacizumab 15 mg/kg q3w for 6 cycles M: Bevacizumab 15 mg/kg q3w for 22 cycles	MTD PFS	I–II

Abbreviations: ADJ, adjuvant chemotherapy; BIS, twice a day; CRR, complete resection rate; M, Maintenance; NACT, neoadjuvant chemotherapy; OS, overall survival; PFS, progression-free survival; q3w, every 3 weeks; MTD, maximum tolerated dose.