Table 1 -.
Baseline demographics and clinical characteristics of the entire cohort, and those meeting (n = 57) or not meeting (n = 118) the primary outcome of endotracheal intubation.
| All patients (n = 175) | Not intubated (n = 118) | Intubated (n = 57) | p-value | |
|---|---|---|---|---|
| Age; years (IQR) | 61 (48, 71) | 58 (46, 70) | 66 (54, 74) | 0.05 |
| Sex; n, (%) | ||||
| Male | 93 (53) | 64 (54) | 29 (51) | 0.68 |
| Female | 82 (47) | 54 (46) | 28 (49) | |
| Race n, (%) | ||||
| White | 94 (54) | 60 (49) | 34 (44) | 0.86 |
| African American | 78 (45) | 55 (47) | 23 (40) | |
| Asian | 2 (1) | 2 (2) | 0 (0) | |
| Other | 1 (1) | 1 (1) | 0 (0) | |
| Ethnicity; n, (%) | ||||
| Hispanic | 9 (5) | 8 (7) | 1 (2) | 0.16 |
| Non-hispanic | 166 (95) | 110 (93) | 56 (98) | |
| Past medical history; n, (%) | ||||
| Hypertension | 102 (58) | 63 (53) | 39 (68) | 0.06 |
| Congestive heart failure | 24 (14) | 17 (14) | 7 (12) | 0.70 |
| Dementia | 16 (9) | 4 (3) | 12 (21) | <0.01 |
| End-stage renal disease | 14 (8) | 13 (11) | 1 (2) | 0.03 |
| Chronic obstructive pulmonary disease | 32 (19) | 18 (15) | 14 (25) | 0.13 |
| Source; n (%) | ||||
| Pneumonia | 57 (33) | 35 (30) | 22 (39) | 0.24 |
| Urinary | 47 (27) | 33 (28) | 14 (26) | 0.63 |
| Intraabdominal | 30 (17) | 20 (17) | 10 (18) | 0.92 |
| Skin/Soft tissue | 15 (8) | 8 (7) | 7 (12) | 0.22 |
| Other | 26 (29) | 22 (19) | 4 (7)23 | 0.05 |
| Labs (enrollment) | ||||
| White blood count; cells/mm3 (IQR) | 12.6 (8.1, 17.7) | 12.4 (8.2, 17.3) | 12.8 (6.8, 20.0) | 0.57 |
| Platelets; cells/mm3 (IQR) | 199 (133, 280) | 199 (136, 284) | 197 (106, 271) | 0.25 |
| Hemoglobin; mg/dL (IQR) | 11.6 (10, 13.4) | 11.5 (10.2, 13.2) | 11.9 (9.8, 13.6) | 0.92 |
| Creatinine; mg/dL (IQR) | 1.8 (1.2, 2.9) | 1.5 (1.0, 2.8) | 2.1 (1.5, 3.4) | 0.03 |
| Total Bilirubin; mg/dL (IQR) | 0.9 (0.6, 1.6) | 0.9 (0.6, 1.8) | 1.0 (0.5, 1.5) | 0.97 |
| SOFA score; n (IQR) | 7 (4, 9) | 6 (4, 8) | 10 (8, 12) | <0.01 |
| Therapies | ||||
| Total intravenous fluids; L (IQR) | 4.0 (2.6, 5.1) | 4.0 (2.5, 5.0) | 4.1 (3.3, 5.3) | 0.14 |
| Outcomes | ||||
| ICU length of stay; days (IQR) | 3 (2, 7) | 2 (1, 4) | 8 (3, 12) | <0.01 |
| Hospital length of stay; days (IQR) | 8 (5, 13) | 7 (5, 11) | 11 (5, 19) | 0.03 |
| In-hospital mortality; n (%) | 36 (21) | 13 (11) | 23 (40) | <0.01 |
*
IQR - Interquartile range; SOFA – Sequential organ failure assessment