Table 3. Factors associated with poor INR control.
Odds Ratio | 95%CI | p-value | |
---|---|---|---|
Socio-demographics | |||
Female | 1.13 | 1.07; 1.20 | <0.001 |
Age 65–75 (ref: age<65) | 0.88 | 0.80; 0.97 | 0.010 |
Age 75 and over (ref: age<65) | 0.87 | 0.80; 0.95 | 0.004 |
Europe (country) (ref: Spain) | 1.23 | 1.05; 1.44 | 0.007 |
Income >18.000e (ref: income ≤18.000) | 0.89 | 0.82; 0.96 | 0.002 |
Comorbidities | |||
Congestive heart failure | 1.19 | 1.12; 1.29 | <0.001 |
Diabetes | 1.14 | 1.08; 1.20 | <0.001 |
Other bleeding | 1.08 | 1.02; 1.14 | 0.011 |
Vascular disease | 1.08 | 1.00; 1.16 | 0.036 |
Dementia | 1.21 | 1.10; 1.35 | <0.001 |
Depression | 1.12 | 1.03; 1.20 | 0.005 |
Alcohol | 1.70 | 1.25; 2.33 | 0.001 |
Healthcare utilisation | |||
Time since Therapy Initiation >6 years | 1.05 | 1.00; 1.11 | 0.047 |
ED visits | 1.04 | 1.03; 1.06 | <0.001 |
Outpatient visits | 1.01 | 1.00; 1.01 | <0.001 |
Specialist visits | 1.02 | 1.01; 1.03 | <0.001 |
Cardiology visits | 0.96 | 0.93; 0.99 | 0.012 |
Neurologic visits | 0.91 | 0.86; 0.95 | <0.001 |
Social care visits | 1.04 | 1.00; 1.09 | 0.017 |
Antiplatelet | 1.11 | 1.00; 1.23 | 0.045 |
n = 22629; LL: -15461.213; p: <0.001; r2: 0.014; C Statistic: 0.579; p (X2 Hosmer-Lemeshow): 0.807.Age (<65, 65–75, >75) and Country (Spain, Europe, Non-Europe, Unknown) are categorical variables. Sex, income, comorbidity variables and Time since Therapy Initiation >6 years are dichotomous variables. Visits are quantitative variables (the variable is number of visits), and accordingly the Odds ratios refer to the odds of presenting a poor INR control with every additional visit.