Skip to main content
. 2019 Feb 12;14(2):e0211681. doi: 10.1371/journal.pone.0211681

Table 4. Factors associated with switching to NOAC.

Odds Ratio 95%CI p-value
Socio-demographics
Non-Europe (country) (ref: Spain) 1,70 1.08;2.67 0.021
Income >18.000e (ref: income ≤18.000) 1,27 1.08;1.49 0.003
Adequate INR control 0.76 0.67;0.86 0.001
Comorbidities
Renal disease 0.69 0.57; 0.83 0.001
Vascular disease 1.34 1.15;1.55 0.001
Healthcare utilisation
Primary Care visits 1.01 1.00; 1.02 0.037
Cardiology visits 1.06 1.01; 1.11 0.018
Time since Therapy initiation>6 years 0.79 0.70; 0.89 0.001

n = 22629; LL: -4282.49; p: <0.0001; r2: 0.012; C Statistic: 0.59; p (X2 Hosmer Lemeshow): 0.573. Adequate INR control: TTR≥65% (ref: TTR<65%). Country (Spain, Europe, Non-Europe, Unknown) is a categorical variable. Income, comorbidity variables and Time since Therapy Initiation >6 years are dichotomous variables. Visits are quantitative variables (the variable is number of visits), and accordingly the Odds ratios refer to the odds of presenting a poor INR control with every additional visit.