Table 1.

Definition of Variables Used in Our Model

Variable	Definition
Vm(t)	membrane potential/potential difference between outer- and inner bulk medium
Φ1(T(t))	potential at the interface between the inner Stern layer and the inner diffuse layer
Φ2(T(t))	surface potential at the inner lipid bilayer
Φ3(T(t))	surface potential at the outer lipid bilayer
Φ4(T(t))	potential at the interface between the outer Stern layer and the outer diffuse layer
σi	intrinsic charge density of the inner side of the lipid bilayer
σo	intrinsic charge density of the outer side of the lipid bilayer
${\mathit{\sigma }}_{\mathit{i}}^{\mathit{s}}$	intrinsic charge density at the interface between the inner Stern layer and the inner diffuse layer
${\mathit{\sigma }}_{\mathit{o}}^{\mathit{s}}$	intrinsic charge density at the interface between the outer Stern layer and the outer diffuse layer
εbi	permittivity of the lipid bilayer
δbi	thickness of the lipid bilayer
ε(T(t))	permittivity of electrolyte medium
δis	thickness of inner Stern layer
δos	thickness of outer Stern layer
δilipid	hydrated size of inner polar lipid head groups
δolipid	hydrated size of outer polar lipid head groups
εis	permittivity of inner Stern layer
εos	permittivity of outer Stern layer
cij(−∞)	concentration of j-th ionic species in the inner bulk medium
coj(∞)	concentration of j-th ionic species in the outer bulk medium
${\mathit{z}}_{\mathit{i}}^{\mathit{j}}$	valence of j-th ionic species in the inner electrolyte
${\mathit{z}}_{\mathit{o}}^{\mathit{j}}$	valence of j-th ionic species in the outer electrolyte
rij	hydrated ionic radius of j-th ionic species in inner electrolyte
roj	hydrated ionic radius of j-th ionic species in outer electrolyte
$\overline{{\mathit{G}}_{{\mathit{K}}^{+}}}$	maximal conductance of the potassium channel
$\overline{{\mathit{G}}_{\mathit{N}{\mathit{a}}^{+}}}$	maximal conductance of the sodium channel
$\overline{{\mathit{G}}_{\mathit{Leak}}}$	maximal conductance of the leak current