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. 2018 Dec 7;116(3):469–476. doi: 10.1016/j.bpj.2018.11.3137

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Major monovalent ionic currents for the Purkinje cell ionic model. Top: Original PRd model is shown. Middle: Adjusted model with TRPM4 channel current and I_eqv subtracted is shown. Bottom: I_TRPM4 is compared to I_Eqv and its constituent currents. The cell was stimulated at pacing cycle length (PCL) = 1000 ms. Kr, rapidly activating delayed rectifier K⁺ current; NCX, Na⁺-Ca²⁺ exchanger current; NaK, Na⁺-K⁺ pump current; NaL2, NaL3, late Na⁺ currents; to1, transient outward current type 1 carried by K⁺. To see this figure in color, go online.