Table 1. Baseline characteristics.
| All Patients (n = 2898) |
hsTnT ≤ 14 ng/L (n = 1267) |
hsTnT > 14 ng/L (n = 1631) |
P-Value | |
|---|---|---|---|---|
| Age (years) | 74 [66–81] | 69 [59–75] | 78 [71–84] | < 0.001 |
| Male sex | 1704/2898 (58.8) | 699/1267 (55.2) | 1005/1631 (61.6) | <0.001 |
| Diabetes mellitus | 785/2887 (27.2) | 222/1263 (17.6) | 563/1624 (34.7) | < 0.001 |
| Arterial hypertension | 2368/2884 (82.1) | 952/1263 (75.4) | 1416/1621 (87.4) | < 0.001 |
| Prior stroke or transient ischemic attack | 298/2887 (10.3) | 89/1265 (7.0) | 209/1622 (12.9) | < 0.001 |
| Peripheral artery disease | 237/2886 (8.2) | 49/1264 (3.9) | 188/1622 (11.6) | < 0.001 |
| Coronary artery disease | 1322/2880 (45.9) | 420/1262 (33.3) | 902/1618 (55.7) | < 0.001 |
| Prior myocardial infarction | 501/2885 (17.4) | 116/1264 (9.2) | 385/1621 (23.8) | < 0.001 |
| Prior percutaneous coronary intervention | 604/2878 (21.0) | 189/1264 (15.0) | 415/1615 (25.7) | < 0.001 |
| Prior coronary artery bypass surgery | 277/2886 (9.6) | 60/1264 (4.7) | 217/1622 (13.4) | < 0.001 |
| Reduced ejection fraction (moderately or severely, < 45%) | 601/1787 (33.6) | 115/669 (17.2) | 486/1118 (43.5) | < 0.001 |
| Valvular atrial fibrillation | 186/2475 (7.5) | 38/1102 (3.4) | 148/1373 (10.8) | < 0.001 |
| Atrial fibrillation in admission electrocardiogram (ECG) | 2628/2891 (90.9) | 1110/1265 (87.7) | 1518/1626 (93.4) | < 0.001 |
| Estimated glomerular filtration rate (eGFR)* (mL/min/1.73 m2) | 71 [51–88] | 82 [67–97] | 59 [41–79] | < 0.001 |
| Severely impaired renal function (eGFR < 30 mL/min/1.73 m2) | 208/2888 (7.2) | 8/1260 (0.6) | 200/1628 (12.3) | < 0.001 |
| Liver cirrhosis | 25/2884 (0.9) | 9/1265 (0.7) | 16/1619 (1.0) | 0.553 |
| Aspartate transaminase (AST) (IU/L) | 27 [20–37] | 25 [20–33] | 28 [21–42] | < 0.001 |
| Aspartate transaminase (AST) > 2 x upper limit of normal (ULN) | 138/2863 (4.8) | 32/1254 (2.6) | 106/1609 (6.6) | < 0.001 |
| Prior major bleeding | 146/2875 (5.1) | 36/1265 (2.8) | 110/1610 (6.8) | < 0.001 |
Data are median [25th, 75th percentiles] or number of patients (%)
* By Modification of Diet in Renal Disease (MDRD) equation