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. 2019 Feb 12;14(2):e0212192. doi: 10.1371/journal.pone.0212192

Fig 6. Gene expression of tendon extracellular-related marker after tenogenic differentiation.

Fig 6

(A) Effect of tenogenic medium on COL1A1, COL3A1 and COMP gene expression in hPL and SF at 1, 3, 7 and 14 days of differentiation (n = 4). Data were normalized against the expression of the housekeeping GAPDH, GUSB and YWHAZ genes and expressed as relative to the calibrator (CAL). * p<0.05, **p<0.01 for TENO vs CTRL cells; $ p<0.05 for differences between time-points. (B) Effect of serum-free media between hPL-TENO and SF-TENO. Data are expressed as average fold increase ± standard deviation compared with the respective CTRL cells (dashed line set at 1). # p<0.05 for hPL versus SF.