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. Author manuscript; available in PMC: 2019 Feb 12.
Published in final edited form as: Cancer Cell. 2019 Jan 31;35(2):283–296.e5. doi: 10.1016/j.ccell.2018.12.013

Figure 3. Atm deletion overcomes Sf3b1 mutation induced-cellular senescence.

Figure 3.

(A) Western blot of senescence markers p16 and p21 in B cells from the different groups of mice are shown. (B) The percentage of B cells undergoing different numbers of cell divisions upon stimulation with LPS+IL4 were shown. Data represent Mean±SD of three replicates. The p values indicate the difference between Sf3b1 MT and other groups in each division point, using ANOVA. (C) Abundance of glutamate and glutamine in splenic B cells from the different mice groups are shown. Data represent Mean±SD of mass spectrometry intensities of three replicates and were analyzed using a one-way ANOVA with the Scheffe correction for multiplicity of testing. See also Figures S4.