Comparison 5. Active versus mixed management of 3rd stage (delayed uterotonic, delayed cord clamping, no controlled cord traction).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Severe primary PPH at time of birth (clinically estimated or measured blood loss ≥ 1000 mL)	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
1.1 Higher‐income setting	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
1.2 Lower‐income setting	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
2 Very severe primary PPH at time of birth (clinically estimated or measured blood loss ≥ 2500 mL)	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
2.1 Higher‐income setting	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
2.2 Lower‐income setting	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
3 Maternal mortality	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
3.1 Higher‐income setting	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
3.2 Lower‐income setting	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
4 Maternal Hb < 9 g/dL at 24‐72 hr	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
4.1 Higher‐income setting	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
4.2 Lower‐income setting	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
5 Admission to neonatal special/intensive care	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
5.1 Higher‐income setting	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
5.2 Lower‐income setting	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
6 Neonatal jaundice requiring phototherapy or exchange transfusion	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
6.1 Higher‐income setting	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
6.2 Lower‐income setting	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
7 Neonatal polycythaemia treated with dilutional exchange transfusion	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
7.1 Higher‐income setting	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
7.2 Lower‐income setting	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
8 Maternal blood transfusion	1	654	Risk Ratio (M‐H, Random, 95% CI)	0.75 [0.17, 3.32]
8.1 Higher‐income setting	1	654	Risk Ratio (M‐H, Random, 95% CI)	0.75 [0.17, 3.32]
8.2 Lower‐income setting	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
9 Therapeutic uterotonics during third stage and/or within 24 hours	1	654	Risk Ratio (M‐H, Random, 95% CI)	0.9 [0.55, 1.48]
9.1 Higher‐income setting	1	654	Risk Ratio (M‐H, Random, 95% CI)	0.9 [0.55, 1.48]
9.2 Lower‐income setting	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
10 Mean length of third stage	1	654	Mean Difference (IV, Random, 95% CI)	‐5.15 [‐5.71, ‐4.59]
10.1 Higher‐income setting	1	654	Mean Difference (IV, Random, 95% CI)	‐5.15 [‐5.71, ‐4.59]
10.2 Lower‐income setting	0	0	Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
11 Manual removal of placenta as defined by study authors	1	654	Risk Ratio (M‐H, Random, 95% CI)	0.67 [0.11, 3.96]
11.1 Higher‐income setting	1	654	Risk Ratio (M‐H, Random, 95% CI)	0.67 [0.11, 3.96]
11.2 Lower‐income setting	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
12 Surgical evacuation of retained products of conception	1	654	Risk Ratio (M‐H, Random, 95% CI)	7.0 [0.36, 134.98]
12.1 Higher‐income setting	1	654	Risk Ratio (M‐H, Random, 95% CI)	7.0 [0.36, 134.98]
12.2 Lower‐income setting	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
13 Birthweight	1	654	Mean Difference (IV, Random, 95% CI)	68.0 [23.87, 112.13]
13.1 Higher‐income setting	1	654	Mean Difference (IV, Random, 95% CI)	68.0 [23.87, 112.13]
13.2 Lower‐income setting	0	0	Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
14 Postnatal maternal mean Hb	1	654	Mean Difference (IV, Random, 95% CI)	0.69 [0.58, 0.80]
14.1 Higher‐income setting	1	654	Mean Difference (IV, Random, 95% CI)	0.69 [0.58, 0.80]
14.2 Lower‐income setting	0	0	Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]