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. 2018 Oct 10;38(9):1489–1507. doi: 10.1038/s41388-018-0532-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — LRP5 was positively correlated with Hsp90ab1 in GC cells and tissues. a Effects of co-transfection of shRNA1 and LRP5 or Hsp90ab1 and siLRP5-#1 on cell invasion and migration by Matrigel invasion assays and Scratch-wound-healing assays. b Graphical illustration of statistical result of co-transfection of shRNA2 and LRP5 or Hsp90ab1 and siLRP5-#1 on cell invasion and migration. c The Hsp90ab1 expression was positively correlated with LRP5 and β-catenin, but it was meaningless correlation with E-cadherin in 36 GC specimens. Representative figures of two cases were shown. Bottom pictures were local magnification of top pictures. d Graphical illustration of the levels of Hsp90ab1 expression that were associated with the levels of β-catenin, LRP5, and E-cadherin in 36 GC specimens