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. 2019 Feb 6;10:53. doi: 10.3389/fmicb.2019.00053

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Copyright © 2019 Sood, Hira, Kumar, Bajaj, Rao, Lal and Shakarad.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparative functional analysis based on COG categories between core and accessory genes in (A) outlier strains (n = 14) and (B) classical strains (n = 64). COG-based binning of core genes and accessory genes. The abscissa denotes different COG functional categories. The ordinate denotes the number of genes in each COG category. Four COG functional categories (RNA processing and modification, Chromatin structure and dynamics, Extracellular structures, and Cytoskeleton) including only one or without homologs in the COG collection are not displayed. Significant enrichment of gene occurrence in the individual category is marked by asterisks (^∗p < 0.05, ^∗∗p < 0.001; FDR < 10% Chi-square test).