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Example of in vitro bortezomib activity (at 2 nM). Below are shown apoptotic cells, which are stained both AnnCy3 (red) and 6-CF (green). For statistical analysis of necrotic/apoptotic/viable cells plasmocytes with diameter 9–12 μm were counted. Cells were stained by immunofluorescent technique as described in Material and methods. Total magnification of 1.500 ×.
