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Plasma melatonin level and brain volumes for patients with Autism spectrum disorder (ASD), their first-degree relatives, and typically developing children (TD).
| ASD | Relatives | TD | R2 (p) | |
|---|---|---|---|---|
| Plasma morning melatonin level (nM) | 0.08 (0.04) |
0.13 (0.06) |
0.14 (0.07) |
0.21(1.3 × 10−11) |
| Pineal gland volume (mm3) | 96.1 (36.7) |
96.2 (35.7) |
108.8 (35.5) |
0.02 (0.10) |
| Total brain volume (cm3) | 1169.1 (123.3) |
1135.7 (119.6) |
1152.7 (88.0) |
0.02 (0.17) |
Data are mean ± standard deviation (SD).
