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. 2016 Sep 12;3(4):162–168. doi: 10.1016/j.ijpam.2016.08.008

Table 1.

Toxicity criteria according to the Common Terminology Criteria for Adverse Events (CTCAE) 2010 guideline.

Grade 1 Grade 2 Grade 3 Grade 4
Hb (g/L) LLN-10 8–10 <8 Life-threatening anemia
ANC(×109/L) LLN-1.5 × 1 1.5–1 1–0.5 <0.5
PLT (×109/L) LLN-75 75–50 50–25 <25
AST and ALT (IU/L) >ULN-3 × ULN 3–5 × ULN 5–20 × ULN >20 × ULN

Hb: Hemoglobin, ANC: Absolute neutrophil count, PLT: Platelet count, AST: Aspartate aminotransferase, ALT: Alanine aminotransferase, LLN: Lower limit of normal, ULN: Upper limit of normal.