Table 6.
Comparison of MTX42h levels in patients with and without hematologic toxicity and distribution with reference to the cycles.
| 2 g/m2 |
Pa | 5 g/m2 |
Pa | |||
|---|---|---|---|---|---|---|
| Hematologic toxicity+ | Hematologic toxicity- | Hematologic toxicity+ | Hematologic toxicity- | |||
| Cycles 1 | 1.04 (0.29–2.02) (n = 8) | 0.53 (0.22–0.90) (n = 6) | >.05 | 0.64 (0.52–1.53) (n = 3) | 0.92 (0.52–1.17) (n = 14) | >.05 |
| Cycles 2 | 0.96 (0.39–1.08) (n = 5) | 0.70 (0.28–0.83) (n = 9) | >.05 | 0.97 (0.34–1.65) (n = 5) | 0.54 (0.41–1.01) (n = 12) | >.05 |
| Cycles 3 | 0.31 (0.22–1.22) (n = 6) | 0.50 (0.48–0.99) (n = 8) | >.05 | 0.95 (0.38–1.62) (n = 6) | 0.45 (0.28–1.06) (n = 11) | >.05 |
| Cycles 4 | 0.56 (0.16–0.95) (n = 4) | 0.58 (0.33–2.23) (n = 10) | >.05 | 0.68 (0.29–1.94) (n = 7) | 0.47 (0.28–0.97) (n = 10) | >.05 |
The first row shows MTX levels at 42 h and the second row shows number of patients.
a
Mann Whitney U- test.