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. 2019 Feb 6;10:130. doi: 10.3389/fmicb.2019.00130

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Copyright © 2019 Xu, Xu, Huang, Qin, Zhang, Zhao, Tu, Shi, Li and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Volcano plot of gene expression changes. The transcriptomes of PBMCs from HAdV-55-infected patients and healthy controls were compared to each other (A–F, the comparison pairs were noted as the caption of every single volcano plot). The x-axis indicates the fold-changes. The y-axis displays the negative logarithm to the base 300 of the t-test p-values. Orange and green dots represent probe sets for transcripts expressed at significantly higher or lower levels in each comparison. HC: healthy control. Silent: patient without any symptoms. Minor: patient with respiratory tract infection symptoms but without pneumonia. Severe: patient with pneumonia.