Fig. 4.

Social behaviors following mifepristone treatment at adulthood. Timeline of the experiment (a). PPS rats showed reduced social preference ratio compared to CTRLs (b). Stressed animals injected with the vehicle exhibited increased total offensive behavior and offensive upright, which were normalized by mifepristone treatment (c and d, respectively). Mifepristone administration reduced the frequency of abnormal attacks in PPS rats (e). N: CTRL vehicle = 14; CTRL mifepristone = 14; PPS vehicle = 12–14 and PPS mifepristone = 13–14. *p < 0.05, **p < 0.01, ***p < 0.001, vs CTRL vehicle, PPS vehicle or main effect of stress. Results are expressed as mean ± SEM