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. 2019 Feb 12;9:1842. doi: 10.1038/s41598-018-37734-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Patients with ventricular-subventricular zone-contacting glioblastoma (VSVZ + GBM) have decreased survival in the TCIA/TCGA-GBM dataset. Kaplan-Meier survival curves depict overall survival (OS, A) and progression free survival (PFS, B). Censored values, representing alive patients or unknown living status, are indicated with tick marks underneath the survival curves. (C,D) Depict forest plots of hazard ratios (HRs) obtained from multivariate Cox overall and progression free survival analyses. *HRs with 95% confidence intervals for age when treated continuously is 1.03 [1.02–1.04], P < 0.001, for OS and **1.02 [1.00–1.03], P = 0.009, for PFS; significance of VSVZ contact remained unchanged.