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. 2019 Feb 12;9:1827. doi: 10.1038/s41598-018-36140-6

Figure 5.

Figure 5

Model of diet-induced obesity and insulin resistance. 8-week-old male C57BL/6 J mice were fed a standard chow (chow) or diabetogenic diet (DD) for 11 weeks. (a) Feeding schematic. (b) Body weight (n = 15). (c) Fasting blood glucose (n = 15). (d) Fixed-dose oral glucose tolerance (n = 11,12) with area under the curve (AUC) quantification. (e) Data represent mean ± SEM; two-way ANOVA with Sidak’s multiple-comparison correction (b) and unpaired t-test (c,e). *P ≤ 0.05, ***P ≤ 0.0005, ****P < 0.0001.